Human FSH Analyte Overview
Human FSH
Also known as Follicle Stimulating Hormone
Follicle-Stimulating Hormone (FSH) is a member of the glycoprotein hormone family secreted by the anterior pituitary gland. It is involved in the development and maintenance of the reproductive system, puberty, and reproduction. FSH activates the aromatase enzyme to convert androgen to estradiol, which ultimately regulates the formation of estrogen hormone. FSH works with Luteinizing Hormone (LH) to regulate female reproduction, particularly ovulation and follicular growth. Mutations of the FSH and FSHR (receptor) genes are linked to a reduction in reproduction function in females. In males, FSH supports spermatogenesis by activating Sertoli cells. Clinically, FSH is often measured to evaluate abnormal puberty timing, fertility issues, and pituitary function. Assisted reproductive treatments commonly uses recombinant FSH to induce follicle growth. Post-reproductive age, high levels of FSH increase the risk for bone loss due to osteoporosis.
Q-Plex™ Details
Species: Human
Assay Type: Sandwich
Sample Type: Urine
Assay Range: 167 – 2.30 mIU/mL
Lower Limit of Detection (LLD): 2.30 mIU/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Catalog #: 463749HU
Features & Requirements
- Measure FSH in 2.25 hours
- Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
- Requires the Q-View™ Imaging System for analysis
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