Human IL-22 Analyte Overview
Human IL-22
Also known as IL-22, Interleukin 22
Interleukin 22 (IL-22) is a powerful and versatile member of the IL-10 cytokine superfamily that mediates cellular inflammatory responses. It is produced by natural killer cells and T cells to activate innate immune responses to bacterial invaders in the epithelial cells that line the gut and respiratory systems, hepatocytes in the liver, and keratinocytes in the skin. It promotes the production of anti-microbial peptides and pro-inflammatory mediators by these cells. It is believed to play a role in coordinating the activities of the innate and adaptive immune responses. It is involved in wound healing on all epithelial surfaces, maintaining the epithelial barrier of the skin, intestines, respiratory tract, and hepatocytes, while also regenerating pancreatic tissue after injury. IL-22 works to regulate metabolic pathways by activating genes that are involved in lipid synthesis. Irregular expression of IL-22 and its signaling pathway are associated with inflammatory and autoimmune diseases including psoriasis, inflammatory bowel disease, and rheumatoid arthritis.
Q-Plex™ Details
Species: Human
Sample Type: Human Serum, EDTA Plasma
Assay Range: 65,000 – 89.16 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Features & Requirements
- Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
- Requires the Q-View™ Imaging System for analysis
Featured Q-Plex Products
Current Retail Kits are Unavailable
Please contact an Account Manager to build a custom kit.
Not Finding What You Need?
Customize a Kit
Not seeing the biomarker or analyte you need? Customize your kit! The Q-Plex™ Custom Assays are fully quantitative ELISA-based Chemiluminescent assay kits allowing the concurrent measurement of up to 18 biomarkers or analytes.
Send in Your Samples
Choose up to 18 different biomarkers that will work best for your research. Send in your samples and let us run them for you.
Contact a Representative
Have questions about the kit or interested in more information? Contact one of our representative to get all your questions answered.
As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.