fbpx

Human MIP-1α Analyte Overview

Human MIP-1α

Also known as MIP-1α, Macrophage Inflammatory Protein-1 alpha, Chemokine Ligand 3, CCL3

Macrophage inflammatory protein 1-alpha (MIP-1α), also known as chemokine (C-C motif) ligand 3 (CCL3), is a cytokine of the immune system involved in inflammation and fever. MIP-1α and its counterpart MIP-1β are produced primarily by macrophages following exposure to a bacterial endotoxin but can also be secreted by other immune cells. It works to activate granulocyte white blood cells and stimulate the production of other pro-inflammatory cytokines. Its presence also limits the production of hematopoietic stem cells. MIP-1α has the ability to induce a rapid onset fever in response to an infection. MIP-1α is capable of suppressing HIV infection since it binds to CCR5, a common HIV coreceptor. MIP-1α is implicated in many diseases, including multiple myeloma, cystic fibrosis, and breast cancer.
Request a Quote

Q-Plex™ Details

Species: Human
Assay Type: Sandwich
Sample Type: Human Serum, EDTA Plasma
Assay Range: 2,000 – 3.57 pg/mL
Lower Limit of Detection (LLD): 1.78 ng/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Catalog #: 467449HU

Features & Requirements

  • Measure MIP-1α in 2.25 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

Featured Q-Plex Products

Human Multiplex Kits

Q-Plex™ Human Cytokine Release Syndrome (16-Plex)

Not Finding What You Need?

Customize a Kit

Not seeing the biomarker or analyte you need? Customize your kit! The Q-Plex™ Custom Assays are fully quantitative ELISA-based Chemiluminescent assay kits allowing the concurrent measurement of up to 18 biomarkers or analytes.

Customize a Kit

Send in Your Samples

Choose up to 18 different biomarkers that will work best for your research. Send in your samples and let us run them for you. 

Get Started

Contact a Representative

Have questions about the kit or interested in more information? Contact one of our representative to get all your questions answered. 

Contact Us

As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.