fbpx

Human PDGF-BB Analyte Overview

Human PDGF-BB

Also known as PDGF, Platelet Derived Growth Factor

Platelet-derived growth factor (PDGF) is a growth factor that mediates growth and cell division. It is a critical regulator of early embryonic development, where it drives the growth of the mesenchyme and later tissue remodeling and morphogenesis. In adults, PDGF promotes blood vessel formation and maintenance, wound healing, survival and regeneration of neurons, and induces of mitosis in connective tissue cells. In the immune system it stimulates neutrophil phagocytosis and inhibits natural killer cell activity. PDGF is chemotactic for fibroblasts, smooth muscle cells, neutrophils and mononuclear cells. The presence of this chemokine is common at the site of healing in damaged tissue, especially connective tissue, where it stimulates collagen synthesis. Clinically, PDGF is often used to heal ulcers, stimulate recovery following orthopedic surgery, and promote soft tissue healing.
Human PDGF-BB Standard Curve
Request a Quote

Q-Plex™ Details

Species: Human
Assay Type: Sandwich
Sample Type: Human Serum, EDTA Plasma
Assay Range: 4,000 – 5.50 pg/mL
Lower Limit of Detection (LLD): 2.20 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Catalog #: 468649HU

Features & Requirements

  • Measure PDGF-BB in 2.25 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

Assay Performance Characteristics

Precision

Intra-assay (n=20)
Average Intra-assay CV: 8%

Sample Concentration (pg/ml) %CV
Sample 1

889.32

 10%
Sample 2 40.79 10%
Sample 3 12.83 4%

 

Inter-assay (n=15)
Average Inter-assay CV: 11%

Sample Concentration (pg/ml) %CV
Sample 1 1020.78 10%
Sample 2 1321.93 13%
Sample 3 678.42 9%

 

Dilutional Linearity

Average percent linearity: 98%
Percent linearity range: 91 – 104%

Dilution Factor % Recovery
Serum HB Serum HD Pooled Plasma Stripped Serum
2 94% 101% 91% 101%
4 102% 91% 104% 104%
8 100% 97% 94% 99%
Human PDGF-BB Linearity

Featured Q-Plex Products

Human Multiplex Kits

Q-Plex™ Human Angiogenesis (9-Plex)

Not Finding What You Need?

Customize a Kit

Not seeing the biomarker or analyte you need? Customize your kit! The Q-Plex™ Custom Assays are fully quantitative ELISA-based Chemiluminescent assay kits allowing the concurrent measurement of up to 18 biomarkers or analytes.

Customize a Kit

Send in Your Samples

Choose up to 18 different biomarkers that will work best for your research. Send in your samples and let us run them for you. 

Get Started

Contact a Representative

Have questions about the kit or interested in more information? Contact one of our representative to get all your questions answered. 

Contact Us

As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.