NHP sIL-1RA Analyte Overview
NHP sIL-1RA
Also known as IL-1Ra, IL-1F3, Interleukin-1 Receptor Antagonist
Interleukin 1 receptor antagonist (IL-1Ra) is an acute phase protein that is a member of the Interleukin 1 family of cytokines. It blocks Interleukin 1 alpha and beta (IL-1α and IL-1β) from binding to the Interleukin 1 receptor type 1. The IL-1 family plays an important role in both adaptive and innate immunity through promoting inflammation, IL-1Ra works to reduce inflammation and fever responses. It is secreted by a variety of cell types, including immune cells, epithelial cells, and adipocytes. It is commonly used in veterinary medicine to calm inflamed soft tissue injuries. A modified version is used in human medicine to treat rheumatoid arthritis. Aberrations in IL-1Ra are associated with schizophrenia and are commonly found in high levels in schizophrenia patients.
Q-Plex™ Details
Species: NHP
Assay Type: Sandwich
Sample Type: Serum/Plasma, Cell Supernatant
Assay Range: 7,000 – 9.6 pg/mL
Lower Limit of Detection (LLD): 4.8 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Features & Requirements
- Data available as fast as 4 hours
- Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
- Requires the Q-View™ Imaging System for analysis of multiplexed chemiluminescent planar-based arrays
Featured Q-Plex Products
Q-Plex™ NHP Anti-Inflammatory Panel 1 (7-Plex)
IL-1RA, IL-2Rα, IL-4, sIL-6R, IL-10, IL-13, TNFRII
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